Cybercriminals are now avoiding detection by infecting computers with fileless malware. In other words, the attacks, launched with the Angler exploit kit, inject malware into the computer’s processes other than files to infect them. By injecting the code into the process rather than the file, it is able to bypass virus detection (which checks the files), facilitate hit-and-run attacks, and allow time for reconnaissance operations before installing a more persistent malware.
Source: ComputerWorld